American Medical Technologist (AMT) Practice Exam

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Which antiseptic is most commonly used to prepare a routine venipuncture site on a patient with no known allergies?

  1. Iodine

  2. 70% isopropyl alcohol

  3. Hydrogen peroxide

  4. Chlorhexidine

The correct answer is: 70% isopropyl alcohol

The most commonly used antiseptic for preparing a routine venipuncture site on a patient with no known allergies is 70% isopropyl alcohol. This antiseptic is widely favored for its effectiveness in rapidly reducing the number of microorganisms on the skin prior to the insertion of a needle. The concentration of 70% is optimal because it contains enough water to slow the evaporation of alcohol, allowing it to remain in contact with the skin long enough to effectively kill bacteria. In practice, isopropyl alcohol is well-tolerated by most patients, making it a preferred choice for many healthcare professionals. It is also quick-drying, which adds to its convenience during a procedure, ensuring that the site is clean and ready for venipuncture without prolonged exposure. Other antiseptics mentioned have different roles or limitations. For example, iodine, while effective, is less commonly used due to potential skin irritation and the risk of allergic reactions in some individuals. Hydrogen peroxide is less favored due to its cytotoxic effects on tissues, which can impede wound healing and cause discomfort. Chlorhexidine is often chosen for its prolonged antimicrobial effects, but it is more commonly reserved for specific circumstances, such as surgical site preparation, rather than routine venipunct